Methurator
note
Estimates sequencing saturation for reduced-representation bisulfite sequencing (RRBS) data.
Methurator is a Python package designed to estimate sequencing saturation for reduced-representation bisulfite sequencing (RRBS) data.
The module parses the methurator_summary.yml file generated by the methurator downsample
command. This file contains:
- Reads summary: Read counts at each downsampling percentage
- CpGs summary: CpG site counts at different coverage thresholds
- Saturation analysis: Model fit results including asymptote and saturation estimates
The module displays key metrics in the General Statistics table and creates saturation curve plots showing how CpG detection changes with sequencing depth.
File search patterns
methurator:
fn: '*methurator_summary.yml'